Pediatric Conditions of the Respiratory System

Subtopic:

Resuscitation of a Newborn

Resuscitation refers to the methods employed to revive a newborn who is experiencing asphyxia, a condition of oxygen deprivation. This critical intervention directly addresses the challenge of birth asphyxia (Devi, Upendra, and Bard, 2017). Essentially, resuscitation involves assisting a baby to begin and maintain breathing.

The neonatal period, encompassing the first 28 days of life, is universally recognized as a time of heightened vulnerability. This period carries the greatest risk of mortality and morbidity due to the significant physiological adjustments newborns undergo. Notably, the day of birth presents the highest immediate danger for the infant (Sajjad, 2012; and WHO, 2015).

APAGAR SCORE

Aims of Management.

The goals of managing a newborn requiring resuscitation are:

  • To initiate and/or restore respiration /breathing: The primary objective is to help the baby begin breathing or to re-establish effective breathing.

  • To prevent infection: Minimizing the risk of infection in the vulnerable newborn period.

  • To prevent other complications: Taking steps to avoid potential health issues that can arise during or after resuscitation.

  • To Prevent hypothermia: Ensuring the baby stays warm, as temperature regulation is crucial.

Requirements

The following equipment and supplies are typically needed for newborn resuscitation:

  • A pair of surgical gloves: To maintain sterility and protect both the caregiver and the infant.

  • Warm baby’s clothes: To dress the baby after stabilization and maintain body temperature.

  • Suction device: Such as a bulb syringe, to clear the airway of fluids.

  • Ventilation bag and mask (ambu bag): Used to provide assisted ventilation if the baby is not breathing adequately.

  • Endotracheal tube: A tube inserted into the trachea to deliver oxygen directly to the lungs. Size typically 1mm for full-term infants or 0.5mm for preterm babies.

  • Laryngoscope: An instrument used to visualize the vocal cords during endotracheal intubation.

  • Nasal gastric tube: May be needed to decompress the stomach.

  • 3 Gallipots: Small, kidney-shaped dishes to hold fluids or small items.

  • 3 Receivers: Containers to collect waste or fluids.

  • Mothers chart: To record important maternal and birth information.

  • Tray containing a gallipot of wet swab, syringes: For cleaning and medication administration.

  • Pediatric stethoscope: To listen to the baby’s heart and lungs.

  • Strapping: To secure the endotracheal tube if needed.

  • Naso prongs (oxygen catheters): Small tubes placed in the nostrils to deliver supplemental oxygen.

Drugs

Medications that may be required during newborn resuscitation include:

  • Naloxone hydrochloride 1mg ampoule 400mg/1ml: An opioid antagonist used to reverse respiratory depression caused by maternal opioid use.

  • Adrenaline (Epinephrine) 1:1000: A medication used to stimulate the heart and increase blood flow.

  • Normal saline 0.9%: An isotonic intravenous fluid for volume replacement.

  • Ringers lactate: Another isotonic intravenous fluid containing electrolytes.

  • Sodium bicarbonate 4.2%: Used to correct metabolic acidosis in certain situations.

  • Dextrose 10%: A glucose solution given intravenously to treat hypoglycemia.

  • Vitamin K: Administered to prevent bleeding.

  • Sterile water: For mixing medications or for rinsing.

Bed side

Essential equipment to have readily available at the bedside includes:

  • Resuscitation table: A firm, flat surface for performing resuscitation.

  • Timer (clock watch): To accurately time interventions and assess the baby’s condition.

  • Light source: To provide adequate illumination for procedures.

  • Oxygen source: A reliable supply of oxygen.

  • Displayed chats for steps: Visual aids outlining the steps of newborn resuscitation.

Principles of Management.

The fundamental principles guiding newborn resuscitation are:

  • Temperature regulation: Maintaining adequate warmth is crucial to prevent hypothermia. Hypothermia can lead to a decreased metabolic rate, adding stress to the newborn.

  • Ensure adequate oxygenation: Providing sufficient oxygen is vital to prevent hypoxia. This involves administering oxygen and monitoring oxygen perfusion. An endotracheal tube may be necessary to deliver oxygen directly.

  • Prevention of hypoglycemia: Regularly monitoring blood glucose levels is important. If a risk of hypoglycemia is identified, dextrose should be administered as prescribed.

Steps for Resuscitation

The sequence of actions in newborn resuscitation can be remembered by the acronym TABCs.

STEP 1

  • Dry the baby, wipe the baby’s mouth with gauze and remove any wet cloth: This helps to prevent heat loss and clear the airway.

STEP 2

  • Clear the air way: Ensuring a clear passage for air is essential.

    • Suck blood or mucus from mouth using a bulb syringe or mucus extractor: Gently remove any obstructions from the mouth and nose.

    • Position baby’s head in a neutral position with head extended: This “sniffing” position helps to open the airway.

    • Place a small towel under the shoulders to maintain the position: This provides support and keeps the head slightly extended.

    • infant resuscitation: This step focuses on establishing an open airway.

STEP 3

  • Support breathing: If the baby is not breathing or is gasping, assisted ventilation is needed.

    • Stand at the baby`s head, apply ambu-bag and a small mask to the baby’s face ensuring that the mask covers the face and mouth to form a seal: A proper seal is necessary for effective ventilation.

    • Give five inflation breaths (each 2-3seconds duration): These initial breaths help to open the lungs.

    • Observe response by looking at the chest movements (chest rising) or increase in the heart rate: Effective ventilation will cause the chest to rise. An increase in heart rate is another positive sign.

    • (if chest does not rise then reapply mask, reposition baby’s head, and suction.): If the chest is not rising, troubleshoot the mask seal, head position, and check for airway obstructions.

    • Continue ventilating at a rate of 30-40 breathes for a minute: Maintain this rate to provide adequate respiratory support.

  • Circulation/External Cardiac Massage: Chest compressions are necessary if the heart rate is dangerously low.

    • Chest compression should be performed when the heart rate is less than 100b/m and falling inspite adequate ventilation: This indicates the need for circulatory support.

    • If no heart beats are recorded after one minute, do external compressions: Immediate action is required if there is no heartbeat.

    • Wrap your palms around the baby`s chest, placing the thumbs / first finger over the lower part of the sternum: This describes the two-thumb encircling technique.

    • Chest is compressed at rate of 100–120 times 1 minute at a ratio of 3 compressions to one ventilation: Maintain this coordinated rhythm of compressions and breaths.

    • Use the thumb to gently compress the chest, depressing it ½ to ¾ inch each time: Apply adequate depth of compression.

    • If in 20 minutes the breathing is not established. Consider intubation: Prolonged lack of spontaneous breathing may necessitate securing the airway with an endotracheal tube.

    • When the infant has no spontaneous breathing then continuous positive pressure ventilation (CPPV) should be started with bag and mask: Providing consistent pressure to keep the airways open.

    • The rate of chest compressions in one minute should be 90 along with 30 PPVs, (3:1), a total of 120 events: This emphasizes the coordination of compressions and positive pressure ventilations.

    • If the heart rate is <60, despite of effective ventilation, chest compression and two intravenous doses of adrenaline (Epinephrine), the sodium bicarbonate 4.2% solution (0.5mmol/ml) can be administered using 2–4ml / kg (1-2mmol/ml) by slow intravenous: This outlines the use of sodium bicarbonate for persistent bradycardia despite other interventions.

Adrenaline (Epinephrine)

Epinephrine administration is considered when the newborn’s heart rate remains below 60 beats per minute despite one minute of effective ventilation and chest compressions. The initial intravenous dose is 0.1 to 0.3 ml/kg of a 1:10,000 solution. This dose can be repeated up to two more times, with 3-minute intervals between doses, if the heart rate does not improve.

10% dextrose

While low blood sugar (hypoglycemia) isn’t a common immediate issue during resuscitation, if the blood glucose level is confirmed to be below 2.5 mmol/L, intravenous administration of 10% dextrose at a dose of 3mls/kg is indicated to correct this. The umbilical vein can be used for administration.

Volume replacement

In infrequent situations, a slow heart rate (bradycardia) will not improve with assisted ventilation and chest compressions. Bradycardia that persists despite these measures and epinephrine administration may suggest the newborn has a low blood volume (hypovolemia). In such cases, an initial dose of 0.9% normal saline at 10 ml/kg can be administered intravenously, often via the umbilical vein, to expand the blood volume.

Naloxone hydrochloride

Naloxone is a medication that counteracts the effects of opioid drugs. It is used when the newborn’s respiratory depression is suspected to be caused by opioid medications given to the mother close to delivery (within approximately 3 hours of birth). The recommended dose is 0.1 to 0.2 mg per kilogram of the baby’s body weight, given intramuscularly. It’s important to note that while helpful in specific situations, naloxone is not a primary emergency resuscitation drug.

Calcium gluconate

In cases of severe bradycardia or when the newborn’s heart and lungs have stopped functioning (cardiopulmonary arrest), calcium gluconate can be considered. A typical dose is 100mg per kilogram of body weight. Additionally, adrenaline (epinephrine) at a dose of 0.1 to 0.5mg/kg can be given concurrently, with administration occurring within 1 minute.

Vitamin K

Vitamin K is routinely given as a preventative measure (prophylaxis) to newborns to protect against bleeding disorders.

Drugs

If there is no heartbeat detected after one full minute of providing breathing support to the baby:

Administer 0.5 mls of a 1:10,000 concentration of adrenaline solution either directly into a vein (intravenously) or through the umbilical vein. In addition, give 1 to 2 mls of a 25% dextrose solution per kilogram of the baby’s weight intravenously.

Continue to assess the baby’s response to the resuscitation efforts by using the Apgar score.

If the newborn responds positively to the resuscitation measures, ensure they are kept warm and transfer them to the Neonatal Intensive Care Unit (NICU) for specialized care.

If the baby is breathing adequately on their own, consistently reassure the mother about her baby’s condition.

If the baby is breathing well, encourage the initiation of breastfeeding. If, despite all efforts, there is no response to the resuscitation attempts, discontinue the resuscitation efforts.