1. Which phase of the cell cycle involves the duplication of the cell's entire genome?
2. The process where cancer cells spread from their original site to form secondary tumors elsewhere is called __________.
3. Antimetabolites are most effective against cancer cells that are:
4. Which category of antineoplastic agents includes substances derived from microbial sources that bind to DNA and block RNA synthesis?
5. A type of malignancy arising from mesenchymal tissues like bone, muscle, or fat is known as a __________.
6. What is the primary mechanism of action for Alkylating Agents?
7. Which specific drug class targets the M phase of the cell cycle by interfering with microtubule function?
8. Imatinib (Gleevec) is indicated for Chronic Myelocytic Leukemia (CML) because it targets which specific type of molecule?
9. The loss of cellular differentiation and organizational structure, a hallmark of cancerous cells, is termed __________.
10. A significant caution for the use of Nilotinib, a targeted therapy agent, is the risk of:
11. Which type of cancer originates in epithelial tissues that line organs and cavities?
12. The formation of new blood vessels, often stimulated by cancerous growths to obtain nutrients, is called __________.
13. Which nursing intervention is crucial for monitoring potential bone marrow suppression caused by many antineoplastic agents?
14. Bortezomib (Velcade) falls under which category of Cancer Cell-Specific Agents?
15. Which cell cycle phase serves as a checkpoint to ensure DNA replication is complete and accurate before cell division begins?
16. __________ agents work by mimicking naturally occurring compounds, thereby interfering with the synthesis of DNA and RNA.
17. Alopecia, a common side effect of many antineoplastic agents, occurs because these drugs affect:
18. Hormones and Hormone Modulators like Tamoxifen are primarily used for cancers that are:
19. What is the key difference between solid tumors and hematological malignancies?
20. During which sub-stage of mitosis do chromosomes align at the cell's equator, orchestrated by microtubules?
