Anatomy and Physiology I

Subtopic:

Cell Structure and Function

Contents

Learning Objectives

  • Define the cell as the basic structural and functional unit of life.
  • Recognize key organelles and describe their functions (e.g. nucleus, mitochondria, ribosomes, lysosomes).
  • Explain the role of the cell membrane in maintaining homeostasis, regulating transport, and communication.
  • Distinguish between cytoplasm and organelles, and identify their roles in metabolism and material transport.
  • Describe the structure and function of each cell organelle, including RER, SER, Golgi apparatus, vesicles, vacuoles, and centrosomes.
  • Understand the roles of cellular components (e.g. chromatin, nucleolus, microtubules, microfilaments, intermediate filaments) in cell division, protein synthesis, and structural support.
  • Apply anatomical terminology related to cell structure in educational and clinical contexts.

 

Cell Structure and Its Functions

Cell: The basic living structural and functional unit of the body. The study of cells is called cytology.

Cell Parts and Functions

Cell Membrane: Separates the cell from its external environment and protects it from injury.

Plasma Membrane: A flexible and selectively permeable barrier that encloses the cell, regulating the movement of substances in and out. It ensures the cell maintains homeostasis by allowing essential nutrients to enter while expelling waste products and harmful substances. It also plays a role in cell signaling and communication.

Cytoplasm: A gel-like substance that fills the cell and surrounds the organelles. It acts as a medium for chemical reactions, providing the necessary environment for metabolic processes and organelle activities. It also helps in the movement of materials within the cell.

Nucleus: The control center of the cell, housing the genetic material (DNA) that dictates all cellular functions, including growth, reproduction, and protein synthesis. It also regulates gene expression, determining which proteins the cell produces.

Nucleolus: Located within the nucleus, it is the site where ribosomal RNA (rRNA) is synthesized and combined with proteins to form ribosomal subunits, which are later transported out to the cytoplasm for protein synthesis.

Chromatin: A complex of DNA and proteins found within the nucleus, it stores genetic information and is responsible for regulating gene activity. During cell division, chromatin condenses into chromosomes to ensure proper DNA distribution.

Mitochondria: Known as the powerhouses of the cell, these organelles generate energy in the form of ATP through cellular respiration. They also play a role in regulating the cell cycle and apoptosis (programmed cell death).

Rough Endoplasmic Reticulum (RER): A network of membranes studded with ribosomes, giving it a rough appearance. It is primarily involved in the synthesis and folding of proteins, which are then transported to the Golgi apparatus for further processing.

Smooth Endoplasmic Reticulum (SER): Lacks ribosomes and is involved in the synthesis of lipids, including oils, phospholipids, and steroids. It also detoxifies drugs and poisons and stores calcium ions, which are crucial for muscle contraction and other cellular activities.

Ribosomes: Small, spherical structures found either floating freely in the cytoplasm or attached to the RER. They are the sites of protein synthesis, where messenger RNA (mRNA) is translated into polypeptide chains.

Golgi Apparatus: A stack of flattened membrane-bound sacs that modify, package, and sort proteins and lipids received from the endoplasmic reticulum. It prepares these molecules for transport to their final destinations, either inside or outside the cell.

Golgi Vesicle: Small membrane-bound sacs that bud off from the Golgi apparatus. They transport proteins and lipids to their target locations, including the plasma membrane or other organelles, and are essential for secretion processes.

Lysosome: A spherical organelle containing digestive enzymes. It breaks down macromolecules, cellular debris, and invading pathogens. Lysosomes also play a role in autophagy, where the cell recycles its own damaged components.

Peroxisome: A small, membrane-bound organelle that contains enzymes for breaking down long-chain fatty acids and toxic substances like hydrogen peroxide. It is crucial for lipid metabolism and maintaining cellular health.

Vacuole: A storage organelle that varies in size depending on the cell type. It stores water, nutrients, and waste products, helping to maintain osmotic balance and providing structural support in plant cells.

Centrosome: A region near the nucleus that organizes microtubules and is critical for cell division. It contains a pair of centrioles in animal cells, which help form the spindle fibers necessary for chromosome separation during mitosis.

Microtubule: Hollow, cylindrical structures made of tubulin proteins. They provide structural support, form the cytoskeleton, and act as tracks for the movement of organelles and vesicles. They are also involved in the separation of chromosomes during cell division.

Microfilament: Thin, thread-like structures composed of actin proteins. They support the cell’s shape, enable cellular movements like crawling or contraction, and are involved in processes such as cytokinesis during cell division.

Intermediate Filament: Rope-like fibers that provide mechanical support to the cell, helping it withstand stress and maintain its structural integrity. They also anchor organelles in place.

Secretory Vesicle: Small sacs that transport molecules, such as proteins and hormones, from the Golgi apparatus to the plasma membrane. These vesicles fuse with the membrane to release their contents outside the cell in processes like exocytosis.

Questions on Cell Structure and Function
  1. Question: What is the basic living structural and functional unit of the body?

    • a) Tissue

    • b) Organ

    • c) Cell

    • d) Molecule

    • Answer: c) Cell

    • Rationale: The cell is the basic living structural and functional unit of the body, as it performs essential life processes.

  2. Question: True or False: The study of cells is called cytology.

    • Answer: True

    • Rationale: Cytology is the branch of biology that studies cells, their structure, function, and chemistry.

  3. Question: What is the function of the cell membrane?

    • a) Stores genetic information

    • b) Separates the cell from its external environment and protects it from injury

    • c) Produces energy for the cell

    • d) Stores food, wastes, and water

    • Answer: b) Separates the cell from its external environment and protects it from injury

    • Rationale: The cell membrane acts as a barrier, controlling the movement of substances in and out of the cell and protecting it from external harm.

  4. Question: Which part of the cell contains raw materials and provides them to cell organelles for their normal functioning?

    • a) Nucleus

    • b) Cytoplasm

    • c) Mitochondria

    • d) Vacuoles

    • Answer: b) Cytoplasm

    • Rationale: The cytoplasm surrounds the organelles and contains raw materials necessary for their functioning.

  5. Question: True or False: The nucleus stores genetic information in chromosomes that can be passed on to daughter cells.

    • Answer: True

    • Rationale: The nucleus contains chromosomes that store genetic information, which is passed on during cell division.

  6. Question: What is the function of chromosomes?

    • a) Produce energy for the cell

    • b) Store food, wastes, and water

    • c) Contain genes that hold hereditary information

    • d) Separate the cell from its external environment

    • Answer: c) Contain genes that hold hereditary information

    • Rationale: Chromosomes contain genes, which are responsible for passing hereditary information from one generation to the next.

  7. Question: Which organelle is known as the powerhouse of the cell?

    • a) Nucleus

    • b) Mitochondria

    • c) Vacuoles

    • d) Cytoplasm

    • Answer: b) Mitochondria

    • Rationale: Mitochondria are known as the powerhouse of the cell because they produce energy through cellular respiration.

  8. Question: True or False: Vacuoles play a role in cell enlargement and store food, wastes, and water.

    • Answer: True

    • Rationale: Vacuoles store food, wastes, and water, and they help maintain the cell’s shape and size.

  9. Question: What are organelles?

    • a) The basic living structural and functional units of the body

    • b) Permanent structures with characteristic morphology that are highly specialized in specific cellular activities

    • c) Substances that surround the organelles and provide raw materials

    • d) Structures that store genetic information

    • Answer: b) Permanent structures with characteristic morphology that are highly specialized in specific cellular activities

    • Rationale: Organelles are specialized structures within cells that perform specific functions necessary for the cell’s survival and operation.

  10. Question: Which part of the cell controls overall cell metabolism and other activities?

    • a) Mitochondria

    • b) Nucleus

    • c) Cytoplasm

    • d) Vacuoles

    • Answer: b) Nucleus

    • Rationale: The nucleus controls overall cell metabolism and activities by regulating gene expression and storing genetic information.

  11. Question: True or False: The cytoplasm is located between the nucleus and the plasma membrane.

    • Answer: True

    • Rationale: The cytoplasm is the substance that fills the space between the nucleus and the plasma membrane, containing organelles and raw materials.

  12. Question: What is the primary function of mitochondria?

    • a) Store genetic information

    • b) Produce energy for various cellular processes

    • c) Separate the cell from its external environment

    • d) Store food, wastes, and water

    • Answer: b) Produce energy for various cellular processes

    • Rationale: Mitochondria produce energy through cellular respiration, making them essential for powering cellular activities.

  13. Question: Which organelle is responsible for storing food, wastes, and water in the cell?

    • a) Nucleus

    • b) Mitochondria

    • c) Vacuoles

    • d) Cytoplasm

    • Answer: c) Vacuoles

    • Rationale: Vacuoles store food, wastes, and water, helping to maintain the cell’s internal environment.

  14. Question: True or False: Chromosomes are located in the cytoplasm.

    • Answer: False

    • Rationale: Chromosomes are located in the nucleus, where they store genetic information.

  15. Question: What is the role of the cell membrane in cellular function?

    • a) Produces energy for the cell

    • b) Stores genetic information

    • c) Controls the movement of substances in and out of the cell

    • d) Stores food, wastes, and water

    • Answer: c) Controls the movement of substances in and out of the cell

    • Rationale: The cell membrane regulates the exchange of substances between the cell and its external environment, maintaining homeostasis.

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